Job Summary:

We are seeking an outstanding Research and Development Scientist, who will be responsible for development, optimization and implementation of mRNA downstream process for mRNA-based drug product manufacturing.

Main Duties and Responsibilities:

  • Development, optimization and implementation of mRNA downstream process for mRNA manufacturing.
  • Performing chromatographic purification of nucleic acids.
  • Performing diafiltration/concentration process of nucleic acids using TFF (tangential flow filtration) technique
  • Collaborating with other research and development teams (formulation team, analytics team, bioassay team) in a multidisciplinary environment
  • Preparation of technical documents, such as method SOP, development reports, experimental plans and reports, scale-up documentation etc.
  • Organization of data, maintaining detailed records, and effective communication of results
  • Supervision of laboratory devices and equipment

Qualifications:

  • MSc in biotechnology, biochemistry or related sciences with 4 years of professional experience; or PhD in chromatography-related scientific field. Industry experience is highly preferred.
  • Hands-on experience with preparative chromatography.
  • Experience with nucleic acid purification, with emphasis on mRNA.
  • Experience with developing chromatographic methods.
  • Experience with gene therapy products and/or mRNA vaccines is a plus
  • Good understanding of chromatographic techniques including affinity chromatography, ion-exchange chromatography, etc.,
  • Experience in Pharmaceutical, CDMO, or cGMP environment preferred.
  • Good understanding of mRNA therapeutic area
  • Very good knowledge of English, spoken and written
  • Excellent oral and written communication skills
  • Strong scientific skills including sound experimental design, data processing and interpretation
  • Self-motivator with an ability to lead the project

What we offer:

  • Stable employment
  • Employment contract
  • Benefits under the Social Fund
  • Subsidies for private medical care
  • A sports card on attractive terms
  • Life insurance on preferential terms
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